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ISSきぼう棟内での細胞培養実験による宇宙放射線影響研究
https://jaxa.repo.nii.ac.jp/records/13311
https://jaxa.repo.nii.ac.jp/records/13311cb2de83b-11d1-4f37-85b0-f53300cf49dc
名前 / ファイル | ライセンス | アクション |
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64297067.pdf (477.7 kB)
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Item type | 会議発表論文 / Conference Paper(1) | |||||
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公開日 | 2015-03-26 | |||||
タイトル | ||||||
タイトル | ISSきぼう棟内での細胞培養実験による宇宙放射線影響研究 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | space radiation, microgravity, human cells, LOH, adaptive response | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
その他のタイトル(英) | ||||||
その他のタイトル | Studies of space radiation influences : An experiment of cell culture in Kibou of ISS | |||||
著者 |
谷田貝, 文夫
× 谷田貝, 文夫× 榎本, 秀一× 高橋, 昭久× 大西, 武雄× 石岡, 憲昭× 大森, 克徳× 嶋津, 徹× 鈴木, ひろみ× Yatagai, Fumio× Enomoto, Shuichi× Takahashi, Akihisa× Onishi, Takeo× Ishioka, Noriaki× Omori, Katsunori× Shimazu, Toru× Suzuki, Hiromi |
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著者所属 | ||||||
理化学研究所 | ||||||
著者所属 | ||||||
理化学研究所 | ||||||
著者所属 | ||||||
奈良県立医科大学 | ||||||
著者所属 | ||||||
奈良県立医科大学 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 | ||||||
著者所属 | ||||||
日本宇宙フォーラム | ||||||
著者所属 | ||||||
日本宇宙フォーラム | ||||||
著者所属(英) | ||||||
en | ||||||
Institute of Physical and Chemical Research (RIKEN) | ||||||
著者所属(英) | ||||||
en | ||||||
Institute of Physical and Chemical Research (RIKEN) | ||||||
著者所属(英) | ||||||
en | ||||||
Nara Medical University | ||||||
著者所属(英) | ||||||
en | ||||||
Nara Medical University | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency (JAXA) | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency (JAXA) | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Space Forum | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Space Forum | ||||||
出版者 | ||||||
出版者 | 宇宙航空研究開発機構宇宙科学研究本部 | |||||
出版者(英) | ||||||
出版者 | Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA) | |||||
書誌情報 |
宇宙利用シンポジウム en : Space Utilization Research: Proceedings of Space Utilization Symposium 巻 25, 発行日 2009-03 |
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会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 第25回宇宙利用シンポジウム(2009年1月14日-15日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス) | |||||
会議概要(会議名, 開催地, 会期, 主催者等)(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | The Twenty-fifth Space Utilization Symposium (January 14-15, 2009: ISAS/JAXA Sagamihara, Japan) | |||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | This paper is aimed to introduce how our developing methodologies for both loss of heterozygosity (LOH) analysis and DNA double-strand break (DSB) repair estimation are applied to detect the biological effects of space radiation. Our space experiments using human cultured cells in Kibou Facility of International Space Station (ISS) are planned to detect mutagenic effects (i), combined effects of radiation with micro gravity (ii), and radioadaptive response (iii). After cell recovery to the earth, we plan to do the following approaches for the above three biological effects: i) an LOH analysis for the mutants induced after the incubation of recovered frozen-cells exposed to low-dose space radiation during the 3 months preservation in ISS, ii) an examination for the existence of combined effects by comparing the mutation inductions between the cells incubated in ISS for ca. 1 week under 1 G and those incubated under micro G, and iii) an estimation of the radioadaptive response from determination of the repair efficiencies of DSB introduced at the specific site of chromosome in the recovered cell. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 形態: カラー図版あり | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10324210 | |||||
資料番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 資料番号: AA0064297067 |