WEKO3
アイテム
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宇宙空間における線虫の老化
https://jaxa.repo.nii.ac.jp/records/13221
https://jaxa.repo.nii.ac.jp/records/132219f92184d-837f-4c8b-be89-fcf7d810ac4f
名前 / ファイル | ライセンス | アクション |
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64730074.pdf (416.3 kB)
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Item type | 会議発表論文 / Conference Paper(1) | |||||
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公開日 | 2015-03-26 | |||||
タイトル | ||||||
タイトル | 宇宙空間における線虫の老化 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
その他のタイトル(英) | ||||||
その他のタイトル | Study of the effects of space flight on the aging of C. elegans | |||||
著者 |
本田, 陽子
× 本田, 陽子× 東端, 晃× 石岡, 憲昭× 田中, 雅嗣× 本田, 修二× Honda, Yoko× Higashibata, Akira× Ishioka, Noriaki× Tanaka, Masashi× Honda, Shuji |
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著者所属 | ||||||
東京都健康長寿医療センター研究所 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構宇宙科学研究本部ISS科学プロジェクト室 | ||||||
著者所属 | ||||||
東京都健康長寿医療センター研究所 | ||||||
著者所属 | ||||||
東京都健康長寿医療センター研究所 | ||||||
著者所属(英) | ||||||
en | ||||||
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency (JAXA) | ||||||
著者所属(英) | ||||||
en | ||||||
ISS Science Project Office, Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS) | ||||||
著者所属(英) | ||||||
en | ||||||
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology | ||||||
著者所属(英) | ||||||
en | ||||||
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology | ||||||
出版者 | ||||||
出版者 | 宇宙航空研究開発機構宇宙科学研究本部 | |||||
出版者(英) | ||||||
出版者 | Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA) | |||||
書誌情報 |
宇宙利用シンポジウム en : Space Utilization Research: Proceedings of Space Utilization Symposium 巻 26, 発行日 2010-02 |
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会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 第26回宇宙利用シンポジウム(2010年1月25日-26日, 宇宙航空研究開発機構宇宙科学研究本部相模原キャンパス) | |||||
会議概要(会議名, 開催地, 会期, 主催者等)(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | The Twenty-sixth Space Utilization Symposium (January 25-26, 2010: ISAS/JAXA Sagamihara, Japan) | |||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | To clarify the effects of the space environment on the aging rate of organisms, we proposed the study of nematode Caenorhabditis elegans in space as a model. We have investigated the effects of a 10-day space flight on an aging marker in the International C. elegans Experiment (ICE)-First, 2004. We examined the change in the polyglutamine (polyQ) aggregation in the transgenic C. elegans of (CAG)35 with yellow fluorescent protein under muscle myosin heavy chain promoter. The polyQ aggregation in space-flown organisms was less than that in the ground control ones. We compared the gene expression levels between the ground control worms and the space-flown worms. Some nerve specific genes were down regulated in space-flown worms. We also examined the effects of the inactivation of these genes on lifespan of C. elegans. We found that the RNAi of each of the 5 genes extended the lifespan. These findings suggest that the aging rate of the space-flown nematodes may be slower than that of the ground control ones. We propose that the further study of aging of C. elegans in space. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 共催: 日本学術会議 | |||||
内容記述(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | joint hosting: The Science Council of Japan | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10324210 | |||||
資料番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 資料番号: AA0064730074 |