WEKO3
アイテム
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細胞に加わる外力を生体信号に変換する過程に関与する分子の探索
https://jaxa.repo.nii.ac.jp/records/13817
https://jaxa.repo.nii.ac.jp/records/13817ff777c19-6cd4-482a-92d0-63fca7e9ddc6
Item type | 会議発表論文 / Conference Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2015-03-26 | |||||
タイトル | ||||||
タイトル | 細胞に加わる外力を生体信号に変換する過程に関与する分子の探索 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | クリノローテーション | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 組織 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 骨芽細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 微小重力 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 培養 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 遺伝子発現 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 生物信号 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | clinorotation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | tissue | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | cell | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | osteoblast | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | microgravity | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | culture | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | gene expression | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | biological signal | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
その他のタイトル(英) | ||||||
その他のタイトル | Conversion of external force on cells into biological signals: A search for participating molecules | |||||
著者 |
高沖, 宗夫
× 高沖, 宗夫× Park, Hyekyeong× 松本, 聡× 芝, 大× 正木, 道子× 行徳, 淳一郎× Takaoki, Muneo× Park, Hyekyeong× Matsumoto, Satoshi× Shiba, Dai× Masaki, Michiko× Gyotoku, Junichiro |
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著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属 | ||||||
宇宙航空研究開発機構 宇宙科学研究本部 | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
著者所属(英) | ||||||
en | ||||||
Japan Aerospace Exploration Agency Institute of Space and Astronautical Science | ||||||
出版者 | ||||||
出版者 | 宇宙航空研究開発機構宇宙科学研究本部 | |||||
出版者(英) | ||||||
出版者 | Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA/ISAS) | |||||
書誌情報 |
宇宙利用シンポジウム 第20回 平成15年度 en : Space Utilization Research: Proceedings of the Twentieth Space Utilization Symposium p. 31-34, 発行日 2004-03 |
|||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Many differences in cellular events have been found between on-orbit cultures and ground controls. These observations suggested that cells could acquire and deal with such environmental information as gravity. However, the molecular mechanism of converting physical force into biological signals had been without any clue. Recently, ion channels have been suggested to be involved in mechanosensing in various tissues. Here, examined were some possibilities if molecular mechanisms known in other tissues work also in bones. It was observed that primary cilia and polycystins, those were reported in renal cells, were also expressed in osteoblast-like cell line. Further studies are in progress to determine if primary cilia and polycystins work as the flow detector of osteoblasts. | |||||
資料番号 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 資料番号: AA0046917012 |