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タイトルMathematical models of continuous flow electrophoresis: Electrophoresis technology
本文(外部サイト)http://hdl.handle.net/2060/19880005639
著者(英)Saville, Dudley A.
著者所属(英)Princeton Univ.
発行日1986-12-01
言語eng
内容記述Two aspects of continuous flow electrophoresis were studied: (1) the structure of the flow field in continuous flow devices; and (2) the electrokinetic properties of suspended particles relevant to electrophoretic separations. Mathematical models were developed to describe flow structure and stability, with particular emphasis on effects due to buoyancy. To describe the fractionation of an arbitrary particulate sample by continuous flow electrophoresis, a general mathematical model was constructed. In this model, chamber dimensions, field strength, buffer composition, and other design variables can be altered at will to study their effects on resolution and throughput. All these mathematical models were implemented on a digital computer and the codes are available for general use. Experimental and theoretical work with particulate samples probed how particle mobility is related to buffer composition. It was found that ions on the surface of small particles are mobile, contrary to the widely accepted view. This influences particle mobility and suspension conductivity. A novel technique was used to measure the mobility of particles in concentrated suspensions.
NASA分類INORGANIC AND PHYSICAL CHEMISTRY
レポートNO88N15021
NASA-CR-179241
NAS 1.26:179241
権利No Copyright
URIhttps://repository.exst.jaxa.jp/dspace/handle/a-is/147690


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