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タイトルSpacelab 1 hematology experiment (INS103): Influence of space flight on erythrokinetics in man
本文(外部サイト)http://hdl.handle.net/2060/19850025380
著者(英)Lange, R. D.; Leach, C. S.; Larkin, E.; Tavassoli, M.; Dunn, C. D. R.; Crosby, W.; Johnson, P. C.; Chen, J. P.
著者所属(英)NASA Johnson Space Center
発行日1985-08-01
言語eng
内容記述An experiment conducted on the 10-day Spacelab 1 mission aboard the ninth Space Shuttle flight in November to December 1983 was designed to measure factors involved in the control of erythrocyte turnover that might be altered during weightlessness. Blood samples were collected before, during, and after the flight. Immediately after landing, red cell mass showed a mean decrease of 9.3 percent in the four astronauts. Neither hyperoxia nor an increase in blood phosphate was a cause of the decrease. Red cell survival time and iron incorporation postflight were not significantly different from their preflight levels. Serum haptoglobin did not decrease, indicating that intravascular hemolysis was not a major cause of red cell mass change. An increase in serum ferritin after the second day of flight may have been caused by red cell breakdown early in flight. Erythropoietin levels decreased during and after flight, but preflight levels were high and the decrease was not significant. The space flight-induced decrease in red cell mass may result from a failure of erythropoiesis to replace cells destroyed by the spleen soon after weightlessness is attained.
NASA分類AEROSPACE MEDICINE
レポートNO85N33693
NAS 1.15:58268
S-548
NASA-TM-58268
権利No Copyright
URIhttps://repository.exst.jaxa.jp/dspace/handle/a-is/155742


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