飛行準備課程学生の＋Gz負荷時における唾液中分泌型免疫グロブリンA及びα-アミラーゼの変化

Abstract

Headward acceleration (+Gz) loads of fighter aircraft pilots are known to induce various kinds of biological responses including sympathetic nervous system activation such as blood pressure and heart rate increment. Recently, salivary secretory immunoglobulin A (sIgA) and α-amylase have been reported to be sensitive biomarkers of sympathetic nervous system activation to reflect psychological and physical stresses. However, the effect of salivary sIgA and α-amylase during +Gz exposure is not well known. The purpose of this study was to investigate the changes of sIgA concentration and α-amylase activity in saliva during +Gz exposures, to compare to the blood pressure and heart rate during +Gz exposure and to do other things. The subjects were 17 male pilot cadets in Japan Air Self-Defense Force. The +Gz exposure profiles consisted of a gradual onset run (0.1G / sec) to the subject's visual end-point (gray-out / black-out) or loss of consciousness, and rapid onset run (1.0G / sec) to the subject's same end-point. Saliva samples were collected 1 hour before, immediately before, immediately after and 1 hour after the +Gz exposures. The levels of blood pressure, heart rate, and salivary α-amylase activity at immediately after the +Gz exposure were higher than those atimmediately before the +Gz exposure. However the Salivary α-amylase activity significant correlated neither with blood pressure nor heart rate. The results suggested that the level of salivary α-amylase activity was influenced during +Gz exposures, but salivary α-amylase activity was not associated with blood pressure and heart rate in the +Gz exposure conditions.