| タイトル | Growth of Streptomyces Hygroscopicus in Rotating-Wall Bioreactor Under Simulated Microgravity Inhibits Rapamycin Production |
| 本文（外部サイト） | http://hdl.handle.net/2060/20000084156 |
| 著者（英） | Fang, A.; Pierson, D. L.; Mishra, S. K.; Demain, A. L. |
| 著者所属（英） | NASA Johnson Space Center |
| 発行日 | 2000-01-01 |
| 言語 | eng |
| 内容記述 | Growth of Streptomyces hygroscopicus under conditions of simulated microgravity in a rotating-wall bioreactor resulted in a pellet form of growth, lowered dry cell weight, and inhibition of rapamycin production. With the addition of Teflon beads to the bioreactor, growth became much less pelleted, dry cell weight increased but rapamycin production was still markedly inhibited. Growth under simulated microgravity favored extracellular production of rapamycin in contrast to a greater percentage of cell-bound rapamycin observed under normal gravity conditions. |
| NASA分類 | Life Sciences (General) |
| 権利 | No Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/226966 |
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