| タイトル | The Antibio experiment |
| 著者（英） | Lapchine, L.; Tixador, R.; Moatti, N.; Gasset, G.; Richoilley, G.; Templier, J. |
| 著者所属（英） | Centre Hospitalier Univ. Purpan |
| 発行日 | 1988-02-01 |
| 言語 | eng |
| 内容記述 | An experiment was flown on Spacelab to confirm the results of the Cytos 2 experiment on Salyut 7, which found an increase in minimal inhibitory concentration in in-flight cultures, i.e., an increase of antibiotic resistance. The 1 g centrifuge on Biorack was also used to differentiate the effects of cosmic rays and microgravity. The antibiotic sensitivity of bacteria cultivated in vitro during orbital flight was studied. The bacteria was E. coli, the antibiotic was Colistin. An increase of antibiotic resistance is observed. Three explanations are offered: stimulation of bacterial proliferation in space; a relationship between the transport of antibiotics into cells and modifications of cellular envelope permeability; and a combined effect of both phenomena. |
| NASA分類 | MATERIALS PROCESSING |
| レポートNO | 88N28159 |
| 権利 | Copyright, Distribution within the U.S. granted by agreement |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/233218 |
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