| タイトル | Combined Effects of Gamma Radiation and High Dietary Iron on Peripheral Leukocyte Distribution and Function |
| 本文（外部サイト） | http://hdl.handle.net/2060/20120007589 |
| 著者（英） | Smith, Scott M.; Zwart, Sara R.; Crucian, Brian E.; Quiriarte, Heather A.; Morgan, Jennifer L. L.; Sams, Clarence F. |
| 著者所属（英） | NASA Johnson Space Center |
| 発行日 | 2012-02-14 |
| 言語 | eng |
| 内容記述 | Both radiation and increased iron stores can independently increase oxidative damage, resulting in protein, lipid and DNA oxidation. Oxidative stress increases the risk of many health problems including cancer, cataracts, and heart disease. This study, a subset of a larger interdisciplinary investigation of the combined effect of iron overload on sensitivity to radiation injury, monitored immune parameters in the peripheral blood of rats subjected to gamma radiation, high dietary iron or both. Specific immune measures consisted of: (1) peripheral leukocyte distribution, (2) plasma cytokine levels and (3) cytokine production profiles following whole blood mitogenic stimulation |
| NASA分類 | Aerospace Medicine |
| レポートNO | JSC-CN-25786 |
| 権利 | Copyright, Distribution as joint owner in the copyright |
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