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タイトルHigh-frequency Electrocardiogram Analysis in the Ability to Predict Reversible Perfusion Defects during Adenosine Myocardial Perfusion Imaging
本文(外部サイト)http://hdl.handle.net/2060/20070021527
著者(英)Schlegel, Todd T.; Pettersson, Jonas; Tragardh, Elin; Carlsson, Marcus; Nilsson, Klas; Pahlm, Olle
著者所属(英)NASA Johnson Space Center; Lund Univ. Hospital
発行日2007-01-01
言語eng
内容記述Background: A previous study has shown that analysis of high-frequency QRS components (HF-QRS) is highly sensitive and reasonably specific for detecting reversible perfusion defects on myocardial perfusion imaging (MPI) scans during adenosine. The purpose of the present study was to try to reproduce those findings. Methods: 12-lead high-resolution electrocardiogram recordings were obtained from 100 patients before (baseline) and during adenosine Tc-99m-tetrofosmin MPI tests. HF-QRS were analyzed regarding morphology and changes in root mean square (RMS) voltages from before the adenosine infusion to peak infusion. Results: The best area under the curve (AUC) was found in supine patients (AUC=0.736) in a combination of morphology and RMS changes. None of the measurements, however, were statistically better than tossing a coin (AUC=0.5). Conclusion: Analysis of HF-QRS was not significantly better than tossing a coin for determining reversible perfusion defects on MPI scans.
NASA分類Aerospace Medicine
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