タイトル | Staphylococcus-mediated T-cell activation and spontaneous natural killer cell activity in the absence of major histocompatibility complex class II molecules |
著者(英) | Chapes, S. K.; Beharka, A. A.; Armstrong, J. W.; Hoynowski, S. M.; Woods, K. M.; Iandolo, J. J.; Spooner, B. S. |
発行日 | 1993-09-01 |
言語 | eng |
内容記述 | We used major histocompatibility complex class II antigen-deficient transgenic mice to show that in vitro natural killer cell cytotoxicity and T-cell activation by staphylococcal exotoxins (superantigens) are not dependent upon the presence of major histocompatibility complex class II molecules. T cells can be activated by exotoxins in the presence of exogenously added interleukin 1 or 2 or in the presence of specific antibody without exogenously added cytokines. |
NASA分類 | Life Sciences (General) |
権利 | Copyright |
URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/296300 |
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