| タイトル | The Hematopoietic Stem Cell Therapy for Exploration of Deep Space |
| 著者（英） | Gonda, Steven R.; Ohi, Seigo; Riley, Danny A.; Fitzgerald, Wendy; Roach, Allana-Nicole |
| 著者所属（英） | NASA Headquarters |
| 発行日 | 2003-07-01 |
| 言語 | eng |
| 内容記述 | It is hypothesized that the hematopoietic stem cell therapy (HSCT) might countermeasure various space-caused disorders so as to maintain astronauts' homeostasis. If this were achievable, the HSCT could promote human exploration of deep space. Using animal models of disorders (hindlimb suspension unloading system and beta-thalassemia), the HSCT was tested for muscle loss, immunodeficiency and space anemia. The results indicate feasibility of HSCT for these disorders. To facilitate the HSCT in space, growth of HSCs were optimized in the NASA Rotating Wall Vessel (RWV) culture systems, including Hydrodynamic Focusing Bioreactor (HFB). |
| NASA分類 | Life Sciences (General) |
| 権利 | Copyright |
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