| タイトル | Protein Crystals and their Growth |
| 著者(英) | Chernov, A. A. |
| 著者所属(英) | NASA Marshall Space Flight Center; BAE Systems |
| 発行日 | 2004-01-01 |
| 言語 | eng |
| 内容記述 | Recent results on binding between protein molecules in crystal lattice, crystal-solution surface energy, elastic properties and strength and spontaneous crystal cracking are reviewed and discussed in the first half of this paper (Sea 2-4). In the second par&, some basic approaches to solubility of proteins are followed by overview on crystal nucleation and growth (Sec 5). It is argued that variability of mixing in batch crystallization may be a source for scattering of crystal number ultimately appearing in the batch. Frequency at which new molecules join crystal lattice is measured by kinetic coefficient and related to the observable crystal growth rate. Numerical criteria to discriminate diffusion and kinetic limited growth are discussed on this basis in Sec 7. In Sec 8, creation of defects is discussed with the emphasis on the role of impurities and convection on macromolecular crystal I;erfection. |
| NASA分類 | Chemistry and Materials (General) |
| 権利 | No Copyright |
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