| タイトル | Inactivation of Semicircular Canals Causes Adaptive Increases in Otolith-driven Tilt Responses |
| 著者（英） | Angelaki, Dora E.; Newlands, Shawn D.; Dickman, J. David |
| 著者所属（英） | Washington Univ. |
| 発行日 | 2002-01-01 |
| 言語 | eng |
| 内容記述 | Growing experimental and theoretical evidence suggests a functional synergy in the processing of otolith and semicircular canal signals for the generation of the vestibulo-ocular reflexes (VORs). In this study we have further tested this functional interaction by quantifying the adaptive changes in the otolith-ocular system during both rotational and translational movements after surgical inactivation of the semicircular canals. For 0.1- 0.5 Hz (stimuli for which there is no recovery of responses from the plugged canals), pitch and roll VOR gains recovered during earth- horizontal (but not earth-vertical) axis rotations. Corresponding changes were also observed in eye movements elicited by translational motion (0.1 - 5 Hz). Specifically, torsional eye movements increased during lateral motion, whereas vertical eye movements increased during fore-aft motion. The findings indicate that otolith signals can be adapted according to compromised strategy that leads to improved gaze stabilization during motion. Because canal-plugged animals permanently lose the ability to discriminate gravitoinertial accelerations, adapted animals can use the presence of gravity through otolith-driven tilt responses to assist gaze stabilization during earth-horizontal axis rotations. |
| NASA分類 | Life Sciences (General) |
| 権利 | Copyright |
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