| タイトル | A novel computational method to simulate non-enzymatic self-replication |
| 著者（英） | Reggia, James A.; Navarro-Gonzalez, Rafael; Chou, Hui-Hsien; Wu, Jayoung |
| 著者所属（英） | NASA Headquarters |
| 発行日 | 1994-06-01 |
| 言語 | eng |
| 内容記述 | Non-enzymatic, template-directed synthesis of oligonucleotides has been extensively studied in the laboratory as a model to understand the kind of chemical processes that might have contributed to the origin of life on Earth. Several oligonucleotides have been shown to catalyze the synthesis of their complements from activated mononucleotides; however, a restricted number of them have been found to self-replicate. Recently we developed an efficient modified cellular automata method that supports the study of self-replicating oligonucleotides. With this method the oligonucleotide molecules are represented as active cells imbedded in a two-dimensional array of inactive cells symbolizing the environment. Random movements and probability-governed chemical reactions occurring in a cellular space can effectively simulate the experimental behavior observed in self-directed replication of oligonucleotides. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 95A63800 |
| 権利 | Copyright |
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