| タイトル | Thermoregulatory responses of rhesus monkeys during spaceflight |
| 著者（英） | Klimovitsky, V.; Magedov, V.; Sulzman, F. M.; Alpatov, A. M.; Moore-Ede, M. C.; Fuller, C. A.; Ferraro, J. S. |
| 著者所属（英） | NASA Headquarters |
| 発行日 | 1992-03-01 |
| 言語 | eng |
| 内容記述 | This study examines the activity, axillary temperature (T(ax)), and ankle skin temperature (Tsk) of two male Rhesus monkeys exposed to microgravity in space. The animals were flown on a Soviet biosatellite mission (COSMOS 1514). Measurements on the flight animals, as well as synchronous flight controls, were performed in the Soviet Union. Additional control studies were performed in the United States to examine the possible role of metabolic heat production in the T(ax) response observed during the spaceflight. All monkeys were exposed to a 24-h light-dark cycle (LD 16:8) throughout these studies. During weightlessness, T(ax) in both flight animals was lower than on earth. The largest difference (0.75 degree C) occurred during the night. There was a reduction in mean heart rate and Tsk during flight. This suggests a reduction in both heat loss and metabolic rate during spaceflight. Although the circadian rhythms in all variables were present during flight, some differences were noted. For example, the amplitude of the rhythms in Tsk and activity were attenuated. Furthermore, the T(ax) and activity rhythms did not have precise 24.0 hour periods and may have been externally desynchronized from the 24-h LD cycle. These data suggest a weakening of the coupling between the internal circadian pacemaker and the external LD synchronizer. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 93A28706 |
| 権利 | Copyright |
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