| タイトル | Ventral horn cell responses to spaceflight and hindlimb suspension |
| 著者（英） | Krasnov, I. B.; Poliakov, I. V.; Jiang, Bian; Roy, Roland R.; Edgerton, V. R. |
| 著者所属（英） | NASA Ames Research Center |
| 発行日 | 1992-08-01 |
| 言語 | eng |
| 内容記述 | Ventral horn cells of the lumbosacral enlargement of the spinal cord were studied focusing on the succinate dehydrogenase (SDH) activity and cross-sectional area of the soma of ventral horn cells which were measured using a computer-aided image-processing system. The relationships between the soma size and SDH activities of lumber ventral horn cells after 14 days of spaceflight (Cosmos 2044) or of hindlimb suspension are considered. Three groups of rats under consideration include control, 14-day spaceflight, and 14-day hindlimb suspension. Data obtained indicate that, compared to the control group, the population distribution of SDH activities in the flight rats shifted toward higher activities, whereas in the suspended rats the distribution shifted toward lower activities. The interactive effects within individual cells showed that there was a higher percentage of small cells with high SDH activities in the flight than in the control or suspended rats. It is suggested that changes in ventral horn cells were due to factors other than simply the absence of weight support. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 92A51486 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/324856 |
|
