| タイトル | Cellular immunity and lymphokine production during spaceflights |
| 著者（英） | Sonnenfeld, G.; Antropova, E. N.; Mandel, A.; Shaffar, L.; Ferrua, B.; Rykova, M. P.; Lesniak, A. T.; Konstantinova, I. V. |
| 著者所属（英） | NASA Ames Research Center |
| 発行日 | 1991-02-01 |
| 言語 | eng |
| 内容記述 | Results are presented on changes in cellular immunity and in the production of lymphokine in spacecrews during spaceflights. Measurements were carried out on blood samples collected from 50 cosmonauts before and after spaceflights of different duration, on board Salyut-6, Salyut-7, or Mir. Additional data were obtained from rats flown on board the Cosmos-1667 and Cosmos-1887 biosatellites. The parameters measured included the PHA responsiveness of T lymphocytes, the activity of T-helper cells and of nonspecific T suppressors, the activity of the so-called natural killer lymphocytes, the production of gamma-interferon, and the cell-surface markers. Results showed that the frequency and the extent of changes in the immunologic resistance of subjects depended on the duration of the flight. However, even after the most prolonged (365 days) spaceflight, the changes observed were mostly of a functional character with subsequent rapid return to normal. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 92A39139 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/326931 |
|
