| タイトル | Transcapillary fluid shifts in tissues of the head and neck during and after simulated microgravity |
| 著者（英） | Tucker, B.; Aratow, M.; Styf, J.; Crenshaw, A.; Parazynski, S. E.; Hargens, A. R. |
| 著者所属（英） | Denver General Hospital|NASA Ames Research Center |
| 発行日 | 1991-12-01 |
| 言語 | eng |
| 内容記述 | To understand the mechanism, magnitude, and time course of facial puffiness that occurs in microgravity, seven male subjects were tilted 6 degrees head down for 8 hr, and all four Starling transcapillary pressures were directly measured before, during , and after tilt. Head-down tilt (HDT) caused facial edema and a significant elevation of microvascular pressures measured in the lower lip. Subcutaneous and intramuscular interstitial fluid pressures in the neck also increased as a result of HDT, while interstitial fluid colloid osmotic pressures remained unchanged. Plasma colloid osmotic pressures dropped significantly after 4 hr of HDT, suggesting a transition from fluid filtration to absorption in capillary beds between the heart and feet during HDT. After 4 hr of seated recovery from HDT, microvascular pressures remained significantly elevated by 5 to 8 mm Hg above baseline values despite a significant HDT diuresis and the orthostatic challenge of an upright, seated posture. During the control (baseline) period, urine output was 46.7 ml/hr; during HDT, it was 126.5 ml/hr. |
| NASA分類 | AEROSPACE MEDICINE |
| レポートNO | 92A18600 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/330442 |
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