| タイトル | Aspects of the Development of Housing for the Spaceflight of Pregnant and Lactating Rats with Neonates |
| 著者（英） | Hinds, William E.; Armstrong, Rachel; Spratt, Shahn; Evans, Juli; Rodriguez, Shari L.; Mayer, David J.; Lemos, Bonnie; Dalton, Bonnie P.; Lane, Philip K.; Navidi, Meena |
| 著者所属（英） | NASA Ames Research Center |
| 発行日 | 1996-01-01 |
| 言語 | eng |
| 内容記述 | Recent and upcoming spaceflights are investigating the effect of weightlessness on developing neural and organ systems. Pregnant rats and dams with neonates have to be accommodated in cages that support the special requirements of these animals. Extensive ground testing of cage concepts, the effect of launch and landing stresses on the maintenance of pregnancy and maternal behavior at different neonatal ages, and techniques for monitoring adaptability to change are discussed. A spaceflight opportunity for the NlH.R3 payload of rat families at three different postnatal ages demonstrated that the survival of very young animals was not good but that older newborns could be returned to Earth in reasonably good health. The development of cages for the Research Animal Holding Facility (RAHF) to support the flight of neonates on Neurolab was continued and incorporated modifications that were demonstrated by the NIH.R3 flight. Other modifications to the RAHF are discussed. Data from biocompatibility and experiment verification testing are presented. |
| NASA分類 | Life Sciences (General) |
| 権利 | No Copyright |
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