| タイトル | Temperature Regulation in Crewmembers After a 115-Day Space Flight |
| 著者（英） | Gonzalez, R.; Fortney, S. M.; Greenleaf, J. E.; Williams, W. J.; Mikhavlov, V.; Lee, S. M. C.; Siconolfi, S. F.; Kobzev, Y. |
| 著者所属（英） | Cosmonaut Training Center; NASA Ames Research Center; Institute of Biomedical Problems; Krug Life Sciences, Inc.; Army Research Inst. of Environmental Medicine; NASA Johnson Space Center |
| 発行日 | 1996-01-01
1996 |
| 言語 | eng |
| 内容記述 | Impaired thermoregulation, which has been observed during exercise following bed rest, may significantly impact crewmembers during space flight operations by decreasing exercise capacity and orthostatic tolerance. Impaired temperature regulation would cause higher levels of core temperature, due to an attenuated cutaneous vasodilatory reflex and sweating response, for a given oxygen consumption. Two mate crewmembers of the Mir 18 mission performed supine cycle exercise se (20 min @ 40% and 20 min @ 65% preflight VO2pk) 145 days preflight and 5 days postflight. Core temperature (Tcore) was measured by an ingestible telemetry pill, skin blood flow (SBF) by laser Doppler velocimetry, and sweat rate (SR) by dew point hygrometry. Tcore at the time of test termination was similar (37.8 C) for both subjects before and after flight despite a shorter test duration (40 vs 28-29 minutes) postflight. The slopes of the SBF/Tcore relationship (Subj 1: 396 vs 214; Subj 2: 704 vs 143 Perfusion Unit/degC) and SR/Tcore relationship (Subj 1: 4.5 vs 2.1; Subj 2: 11.0 vs 3.6mg/min/sq cm/degC) were reduced postflight. Tcore thresholds for both SR (Subj 1: 37.4 vs 37.6; Subj 2: 37.6 vs 37.6 C) and SBF (Subj 1: 37.3 vs 37.5; Subj 2: 37.6 vs 37.7 C) were similar pre- to postflight. For these 2 crewmembers, it appeared that thermoregulation during exercise was impaired as evidenced by compromised heat loss responses after long-duration space flight. |
| NASA分類 | Aerospace Medicine |
| 権利 | Copyright |
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