| タイトル | Effects of Radiation on Rat Retina after 18 days of Space Flight |
| 著者（英） | Turnbill, C.; Dayhoff, D.; Philpott, D.; McGourty, J.; Savick, L.; Corbett, R.; Harrison, G.; Lee, R.; Black, S. |
| 著者所属（英） | NASA Ames Research Center |
| 発行日 | 1978-08-01 |
| 言語 | eng |
| 内容記述 | Although cumulative effects an retina from low-dose radiation during prolonged spaceflight are not known, ary impairment of vision could set limits for spaceflight duration. Cosmic rays are now considered to be the cause of the "light flashes" seen during spaceflight by activating retina cells as they pass through the photoreceptors. Previous studies have also shown retinal cellular alterations and cell necrosis from high-energy, particle (HZE) radiation. Ten rats, 5 centrifuged during flight (FC) to simulate gravity and 5 in-flight stationary (FS) experiencing hypogravity, orbited Earth for 18.5 days on Cosmos 936. The animals were sacrificed 25 days post-recovery and the eyes flown to Ames Res. Ctr. The pattern of cell necrosis in the retinas from the FC group showed the same response to radiation as the FS. This would indicate that hypogravity was not a factor in the observed results. Also the cellular response in the retinas exposed in the Berkeley accelerator again matched both the FC and FS eyes. Thus all three conditions provide comparable changes and indicate HZE particles as the possible cause of the cellular alterations, channels, and breakdown. |
| NASA分類 | Life Sciences (General) |
| 権利 | No Copyright |
|
