| タイトル | Effects of interferon-gamma and tumor necrosis factor-alpha on macrophage enzyme levels |
| 著者（英） | Pierangeli, Silvia S.; Sonnenfeld, Gerald |
| 著者所属（英） | Louisville Univ. |
| 発行日 | 1989-01-01 |
| 言語 | eng |
| 内容記述 | Murine peritoneal macrophages were treated with interferon-gamma (IFN-gamma) or tumor necrosis factor-alpha (TNF). Measurements of changes in acid phosphatase and beta-glucuronidase levels were made as an indication of activation by cytokine treatment. IFN-gamma or TNF-gamma treatment resulted in a significant increase in the activities of both enzymes measured in the cell lysates. This increase was observable after 6 h of incubation, but reached its maximum level after 24 h of incubation. The effect of the treatment of the cell with both cytokines together was additive. No synergistic effect of addition of both cytokines on the enzyme levels was observed. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 89A37674 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/363642 |
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