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タイトルInhibited interferon-gamma but normal interleukin-3 production from rats flown on the Space Shuttle
著者(英)Williams, Joann; Lyte, Mark; Gould, Cheryl L.; Mandel, Adrian D.; Sonnenfeld, Gerald
著者所属(英)NASA Ames Research Center|Louisville Univ.|Pittsburgh Univ.
発行日1987-10-01
言語eng
内容記述Rats were flown on Space Shuttle SL-3 for one week. When spleen cells were removed from these rats and challenged with concanavalin-A, interferon-gamma production was severely inhibited, while interleukin-3 production was unaffected compared to ground-based control rats. These data indicate that there is a defect in interferon-gamma production in rats that have been exposed to spaceflight. This defect could contribute to, and be one reason for, immunosuppression observed after spaceflight.
NASA分類LIFE SCIENCES (GENERAL)
レポートNO88A15343
権利Copyright
URIhttps://repository.exst.jaxa.jp/dspace/handle/a-is/374127


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