タイトル | Inhibited interferon-gamma but normal interleukin-3 production from rats flown on the Space Shuttle |
著者(英) | Williams, Joann; Lyte, Mark; Gould, Cheryl L.; Mandel, Adrian D.; Sonnenfeld, Gerald |
著者所属(英) | NASA Ames Research Center|Louisville Univ.|Pittsburgh Univ. |
発行日 | 1987-10-01 |
言語 | eng |
内容記述 | Rats were flown on Space Shuttle SL-3 for one week. When spleen cells were removed from these rats and challenged with concanavalin-A, interferon-gamma production was severely inhibited, while interleukin-3 production was unaffected compared to ground-based control rats. These data indicate that there is a defect in interferon-gamma production in rats that have been exposed to spaceflight. This defect could contribute to, and be one reason for, immunosuppression observed after spaceflight. |
NASA分類 | LIFE SCIENCES (GENERAL) |
レポートNO | 88A15343 |
権利 | Copyright |
URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/374127 |
|