| タイトル | Failure of metoclopramide to control emesis or nausea due to stressful angular or linear acceleration |
| 著者(英) | Kohl, Randall Lee |
| 著者所属(英) | Universities Space Research Association|NASA Johnson Space Center |
| 発行日 | 1987-02-01 |
| 言語 | eng |
| 内容記述 | Orally administered metoclopramide (REGLAN) at doses of 10 or 20 mg, 75 min prior to either stressful linear acceleration (parabolic flight) or cross-coupled accelerative semicircular canal stimulation in a rotating chair was evaluated for its ability to prevent emesis or nausea II, respectively. Although metoclopramide is an effective antiemetic agent that enhances gastric emptying and prevents cancer chemotherapy-induced emesis, it was not possible to demonstrate any significant (p less than 0.05) effects of this drug on motion sickness. |
| NASA分類 | AEROSPACE MEDICINE |
| レポートNO | 87A31695 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/378884 |
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