| タイトル | Growth and development of mice and rats conceived and reared at different G-intensities during chronic centrifugation |
| 著者（英） | Corrales, J.; Solgaard, L.; Monson, C. B.; Oyama, J. |
| 著者所属（英） | NASA Ames Research Center |
| 発行日 | 1985-12-01 |
| 言語 | eng |
| 内容記述 | Prenatal and postnatal growth of rats conceived and reared at different G-intensities from 1.0G (earth gravity) to a maximum of 2.03G were compared. Prenatal growth was not generally impaired but the lung/body mass ratio of 22-day old fetuses at 2.03G was decreased significantly compared to 1.06 controls. Survival of neonatal rats was substantially reduced at 1.71G and 2.03G. Postnatal growth was decreased at the higher G-intensities and showed smaller or no effects at the lower G-intensities. Comparisons of organ/body mass ratios of hyper-G and 1.0G rats at 9 wks of age showed relatively few differences at the lower G-intensities. Postnatal growth of mice at 2.03G was suppressed during the neonatal period but recovered later so that after 9 wks the body mass of females reached and of males approached controls. Results of this preliminary study clearly show the influence of body mass in scaling the effects of hyper-G on the growth and development of and between different animal species. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 86A30403 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/385657 |
