| タイトル | Immersion diuresis without expected suppression of vasopressin |
| 著者（英） | Keil, L. C.; Greenleaf, J. E.; Spaul, W. A.; Kravik, S. E.; Wong, N.; Silver, J. E. |
| 著者所属（英） | NASA Ames Research Center |
| 発行日 | 1984-07-01 |
| 言語 | eng |
| 内容記述 | There is a shift of blood from the lower parts of the body to the thoracic circulation during bed rest, water immersion, and presumably during weightlessness. On earth, this central fluid shift is associated with a profound diuresis. However, the mechanism involved is not yet well understood. The present investigation is concerned with measurements regarding the plasma vasopressin, fluid, electrolyte, and plasma renin activity (PRA) responses in subjects with normal preimmersion plasma vasopressin (PVP) concentration. In the conducted experiments, PRA was suppressed significantly at 30 min of immersion and had declined by 74 percent by the end of the experiment. On the basis of previously obtained results, it appears that sodium excretion during immersion may be independent of aldosterone action. Experimental results indicate that PVP is not suppressed by water immersion in normally hydrated subjects and that other factors may be responsible for the diuresis. |
| NASA分類 | AEROSPACE MEDICINE |
| レポートNO | 84A43822 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/396858 |
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