| タイトル | Sensitivity of bone cell populations to weightlessness and simulated weightlessness |
| 著者（英） | Roberts, W. E.; Morey-Holton, E. R.; Gonsalves, M. R. |
| 著者所属（英） | NASA Ames Research Center |
| 発行日 | 1984-07-01 |
| 言語 | eng |
| 内容記述 | A rat suspension model for simulating certain aspects of weightlessness is discussed. Perturbations in physiological systems induced by this head down suspension model are verified by flight data. Findings of a suppression of osteoblast differentiation help explain the inhibition of bone formation inflight and during Earth-bound simulations. Since the anatomical site for these studies was in the maxilla, which is gravity loaded but non weightbearing in ground-based simulations, the similarity of bone cell kinetic changes, both inflight and in the ground-based model, suggest that fluid shifts rather than unloading may play an important role in bone alterations, at least at this sampling site. |
| NASA分類 | AEROSPACE MEDICINE |
| レポートNO | 84N34151 |
| 権利 | No Copyright, Distribution within the U.S. granted by agreement |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/401101 |
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