| タイトル | Fluid shifts and muscle function in humans during acute simulated weightlessness |
| 著者（英） | Akeson, W. H.; Hargens, A. R.; Mubarak, S. J.; Tucker, B. J.; Gollnick, P. D.; Tipton, C. M. |
| 著者所属（英） | California Univ.|Iowa Univ.|Washington State Univ. |
| 発行日 | 1983-04-01 |
| 言語 | eng |
| 内容記述 | The acute effects of simulated weightlessness on transcapillary fluid balance, tissue fluid shifts, muscle function, and triceps surface reflex time were studied in eight supine human subjects who were placed in a 5 degrees head-down tilt position for 8 hr. Results show a cephalic fluid shift from the legs as indicated by facial edema, nasal congestion, increased urine flow, decreased creatinine excretion, reduced calf girth, and decreased lower leg volume. The interstitial fluid pressure in the tibialis anterior muscle and subcutaneous tissue of the lower leg was found to fall significantly, while other transcapillary pressures (capillary and interstitial fluid colloid osmotic pressures) were relatively unchanged. The total water content of the soleus muscle was unchanged during the head-down tilt. After head-down tilt, isometric strength and isokinetic strength of the plantar flexors were unchanged, while the triceps surae reflex time associated with plantar flexion movement slowed slightly. These results demonstrate a dehydration effect of head-down tilt on muscle and subcutaneous tissue of the lower leg that may affect muscle function. |
| NASA分類 | AEROSPACE MEDICINE |
| レポートNO | 83A30501 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/404474 |
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