| タイトル | Evidence for arrested bone formation during spaceflight |
| 著者（英） | Baylink, D. J.; Morey, E. R.; Turner, R. T.; Duvall, P.; Bobyn, J. D.; Spector, M. |
| 著者所属（英） | Medical Univ. of South Carolina|NASA Ames Research Center|Veterans Administration Hospital |
| 発行日 | 1982-01-01 |
| 言語 | eng |
| 内容記述 | Addressing the question of whether the bone formed in space is unusual, the morphology of bone made at the tibial diaphysis of rats before, during, and after spaceflight is studied. Evidence of arrest lines in the bone formed in space is reported suggesting that bone formation ceases along portions of the periosteum during spaceflight. Visualized by microradiography, the arrest lines are shown to be less mineralized than the surrounding bone matrix. When viewed by scanning electron microscopy, it is seen that bone fractures more readily at the site of an arrest line. These observations are seen as suggesting that arrest lines are a zone of weakness and that their formation may result in decreased bone strength in spite of normalization of bone formation after flight. The occurrence, location, and morphology of arrest lines are seen as suggesting that they are a visible result of the phenomenon of arrested bone formation. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 82A40767 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/409440 |
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