| タイトル | Effect of weightlessness and centrifugation on red cell survival in rats subjected to space flight |
| 著者（英） | Landaw, S. A.; Serova, L. V.; Leon, H. A. |
| 著者所属（英） | NASA Ames Research Center|Ministry of Health of the USSR|Veterans Administration Hospital |
| 発行日 | 1980-10-01 |
| 言語 | eng |
| 内容記述 | Rats were flown aboard the Soviet biosatellite Cosmos 936 for 18.5 d during August, 1977. Five rats were subjected to near-weightless space flight, as with Cosmos 782, and five rats were subjected to a 1-G force via an on-board centrifuge. These rats and three control groups were injected with 2-(C-14) glycine 19 d preflight. The flight rats were recovered from orbit after 18.5 d of space flight. Erythrocyte hemolysis and lifespan were evaluated in the five groups of rats by quantitation of radioactive carbon monoxide exhaled in the breath which arises from the breakdown of the previously labeled hemoglobin. The results support the previous findings wherein hemolysis was found to increase as a result of weightless space flight. A comparison to the centrifuged animals indicates that artificial gravity attenuates the effect of weightlessness on hemolysis and appears to normalize the hemolytic rate in the early postflight period. |
| NASA分類 | LIFE SCIENCES (GENERAL) |
| レポートNO | 81A12232 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/419019 |
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