タイトル | Spatial distribution of pulmonary blood flow in dogs in increased force environments |
著者(英) | Chevalier, P. A.; Sass, D. J.; Greenleaf, J. F.; Ritman, E. L.; Wood, E. H. |
著者所属(英) | Mayo Clinic|Mayo Foundation |
発行日 | 1978-03-01 |
言語 | eng |
内容記述 | Spatial distribution of pulmonary blood flow during 2- to 3-min exposures to 6-8 Gy acceleration was studied, using radioactive microspheres in dogs, and compared to previously reported 1 Gy control distributions. Isotope distributions were measured by scintiscanning individual 1-cm-thick cross sections of excised, fixed lungs. Results indicate: (1) the fraction of cardiac output traversing left and right lungs did not change systematically with the duration and magnitude of acceleration; but (2) the fraction is strongly affected by the occurrence or absence of fast deep breaths, which cause an increase or decrease, respectively, in blood flow through the dependent lung; and (3) Gy acceleration caused a significant increase in relative pulmonary vascular resistance (PVR) in nondependent and dependent regions of the lung concurrent with a decrease in PVR in the midsagittal region of the thorax. |
NASA分類 | LIFE SCIENCES (GENERAL) |
レポートNO | 78A29032 |
権利 | Copyright |
URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/433363 |
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