| タイトル | Evaluation of a new antinauseant drug for the prevention of motion sickness |
| 著者（英） | Graybiel, A.; Knepton, J. |
| 著者所属（英） | Naval Aerospace Medical Research Lab. |
| 発行日 | 1977-09-01 |
| 言語 | eng |
| 内容記述 | The new drug, AHR 5645B, together with other drugs was evaluated in tests, conducted with eight male subjects, concerning its ability to prevent motion sickness. It was found that AHR 5645B, used in doses of 20, 50, and 100 mg, was not efficacious in preventing experimental motion sickness. A combination of 50 mg meclizine and 25 mg ephedrine sulfate produced the best results. Favorable results were also obtained with a combination of 12.5 mg promethazine hydrochloride and 12.5 mg ephedrine sulfate. The findings in the reported experiment point to the difficulty of identifying a highly efficacious antimotion sickness drug for everyone. |
| NASA分類 | AEROSPACE MEDICINE |
| レポートNO | 77A49837 |
| 権利 | Copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/436464 |
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