| タイトル | Oscillation of Angiogenesis and Vascular Dropout in Progressive Human Vascular Disease |
| 本文（外部サイト） | http://hdl.handle.net/2060/20150010324 |
| 著者（英） | Parsons-Wingerter, Patricia |
| 著者所属（英） | NASA Glenn Research Center |
| 発行日 | 2010-02-08 |
| 言語 | eng |
| 内容記述 | When analyzed by VESsel GENeration Analysis (VESGEN) software, vascular patterns provide useful integrative read-outs of complex, interacting molecular signaling pathways. Using VESGEN, we recently discovered and published our innovative, surprising findings that angiogenesis oscillated with vascular dropout throughout progression of diabetic retinopathy, a blinding vascular disease. Our findings provide a potential paradigm shift in the current prevailing view on progression and treatment of this disease, and a new early-stage window of regenerative therapeutic opportunities. The findings also suggest that angiogenesis may oscillate with vascular disease in a homeostatic-like manner during early stages of other inflammatory progressive diseases such as cancer and coronary vascular disease. |
| NASA分類 | Aerospace Medicine; Mathematical and Computer Sciences (General); Life Sciences (General) |
| レポートNO | E-661298 |
| 権利 | No Copyright |
