| タイトル | Exposure to Deep Space Exploration and EVA Atmospheres (Hypoxia/Hyperoxia) - Effect on Hematologic, Immunologic, and Oxidative Stress and Damage Parameters in Astronauts - A Flight Study on ISS |
| 本文（外部サイト） | http://hdl.handle.net/2060/20150001876 |
| 著者（英） | Chouker, Alexander; Simpson, Richard; Crucian, Brian; Otto, Christian; Goodwin, Thomas; Pierson, Duane; Basner, Mathias |
| 発行日 | 2015-01-13 |
| 言語 | eng |
| 内容記述 | Spaceflight has been established to profoundly dysregulate immunity. In various Terrestrial situations hypoxia has also been demonstrated to negatively influence immunity. NASA has selected 8.2 PSI, 34% Oxygen as the proposed atmosphere for exploration-class deep space missions. It is unknown how the proposed hypoxic atmosphere will further influence crew physiology and possibly enhance crew clinical risk during exploration class deep space missions. The primary purpose of the study is to determine both acute and chronic alterations in crewmember hematologic, immunologic (both innate + adaptive) and oxidative stress parameters, with cognition and VIIP, during exposure to the proposed exploration atmosphere during spaceflight. |
| NASA分類 | Man/System Technology and Life Support; Aerospace Medicine |
| レポートNO | JSC-CN-32661 |
| 権利 | Copyright, Distribution as joint owner in the copyright |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/559425 |
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