| タイトル | Quantitative Evaluation of the Regional Dynamic Function of Hepatocytes after Living Donor Liver Transplantation Using 99mTc-GSA: A Preliminary Report |
| 本文（外部サイト） | http://naosite.lb.nagasaki-u.ac.jp/dspace/bitstream/10069/9280/1/acta49_04_137.pdf |
| 参考URL | http://hdl.handle.net/10069/9280 |
| 著者（英） | Ohno, Yasuharu; Ishida, Haruo; Hayashi, Akira; Kamagata, Shoichiro; Hirobe, SeiichiFuchimoto, Yasushi; Ishii, Katsumi |
| 発行日 | 2004-12 |
| 刊行物名 | Acta medica Nagasakiensia |
| 巻 | 49 |
| 号 | 4 |
| 開始ページ | 137 |
| 終了ページ | 141 |
| 刊行年月日 | 2004-12 |
| 言語 | eng |
| 内容記述 | In this study, we attempted to evaluate the dynamic function of graft livers after a living donor liver transplantation (LDLT) using technetium-99m-galactosyl-human serum albumin (99mTc-GSA) scintigraphy. We performed 99mTc-GSA scintigraphy 24 times in a total of 15 pediatric patients following LDLT. The age at examination (mean±standard deviation) was 7.3±5.54 years. The median interval between the examination and LDLT was 42 months. We converted the time activity curve for the graft to a horizontal mirror image curve and calculated the mean transit time (MTT) and depicted the functional image. The whole graft MTT showed a significant correlation with the receptor index (r=?0.528, p=0.014), total bilirubin (r=0.470, p=0.032) and cholinesterase (r=?0.641, p<0.014), and a marginally significant correlation with the clearance index (r=0.424, p=0.056). The functional image was quite useful for making a visual evaluation of the regional dynamic distribution of 99mTc-GSA in the graft. We thus consider this modality a valuable adjunct for evaluating the regional deterioration of the dynamic function of the liver following liver transplantation. |
| キーワード | Livertransplantation; Asialoglycoproteinreceptorscintigraphy; Dynamicfunctionoftheliver |
| 資料種別 | Departmental Bulletin Paper |
| 著者版フラグ | publisher |
| ISSN | 00016055 |
| URI | https://repository.exst.jaxa.jp/dspace/handle/a-is/612901 |
