JAXA Repository / AIREX 未来へ続く、宙(そら)への英知

このアイテムに関連するファイルはありません。

タイトルBiosensors for Real-Time Monitoring of Radiation-Induced Biologic Effects in Space
本文(外部サイト)http://hdl.handle.net/2060/20020070827
著者(英)Kukowska-Latallo, Jolanta; Majoros, Istvan; Balogh, Lajos; Baker, James R.; delaiglesia, Felix; Keszler, Balazs; Beeson, Nicholas W.; Myc, Andrzej; Norris, Theodore
著者所属(英)Michigan Univ.
発行日2002-08-01
言語eng
内容記述This work seeks to develop cellular biosensors based on dendritic polymers. Nanoscale polymer structures less than 20 nm in diameter will be used as the basis of the biosensors. The structures will be designed to target into specific cells of an astronaut and be able to monitor health issues such as exposure to radiation. Multiple components can be assembled on the polymers including target directors, analytical devices (such as molecular probes), and reporting agents. The reporting will be accomplished through fluorescence signal monitoring, with the use of multispectral analysis for signal interpretation. These nanosensors could facilitate the success and increase the safety of extended space flight. The design and assembly of these devices has been pioneered at the Center for Biologic Nanotechnology in the University of Michigan. This period, synthesis of the test-bed biosensors continued. Studies were performed on the candidate fluorescent dyes to determine which might be suitable for the biosensor under development. Development continued on producing an artificial capillary bed as a tool for the use in the production of the fluorescence signal monitor. Work was also done on the in vitro multispectral analysis system, which uses the robotic microscope.
NASA分類Life Sciences (General)
レポートNONAS2-02069-4
権利No Copyright
URIhttps://repository.exst.jaxa.jp/dspace/handle/a-is/91278


このリポジトリに保管されているアイテムは、他に指定されている場合を除き、著作権により保護されています。